JNTU III-I B PHARM PHARMACEUTICAL BIOCHEMISTRY QUESTION PAPER, NOVEMBER 2010

Code No : R7401
JAWAHARLAL TECHNOLOGICAL UNIVERSITY, HYDERABAD
III B.Pharmacy I Semester Regular Examinations, November 2010

PHARMACEUTICAL BIOCHEMISTRY
Time : 3 Hours Max.Marks : 80
Answer any FIVE questions.
All questions carry equal marks.
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1.a) What do you mean by facilitated diffusion across cell membrane and explain
about it.
b) What is the difference between endocytosis and exocytosis.

2.a) What is the importance of Rotary motor model for ATP generation.
b) What is the difference between high-energy phosphates and low-energy phosphates,
Give examples for them.

3. What are enzymes? Write their properties and mechanisms of action.

4. Write short note on
a) Mutarotation.
b) Reducing sugars.
c) Epimers.
d) Mucopolysaccharides.

5.a) What is glucose tolerance test.
b) What are the significances of glycolysis.
c) Glycogenolysis.

6.a) Discuss the Nutritional and metabolic disorders of protein metabolism.
b) Write note on metabolic disorders of Valine.

7.a) What are the major sites of cholesterol Bio-synthesis?
b) In which pathological condition ketone bodies appear in urine.
c) What is the role of carnitine in fatty acid metabolism?

8. Write a note on
a) Inhibition of PG-Synthesis.
b) Degradation of Prostaglandins.

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